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Robert J Fram Selected Research

tasidotin

11/2005A phase I study of the dolastatin-15 analogue tasidotin (ILX651) administered intravenously daily for 5 consecutive days every 3 weeks in patients with advanced solid tumors.
11/2005Phase I and pharmacokinetic study of the dolastatin-15 analogue tasidotin (ILX651) administered intravenously on days 1, 3, and 5 every 3 weeks in patients with advanced solid tumors.

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Robert J Fram Research Topics

Disease

4Neoplasms (Cancer)
05/2012 - 11/2005
3Fatigue
07/2021 - 11/2005
2Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic)
01/2022 - 01/2018
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2022 - 01/2018
2Myelodysplastic Syndromes (Myelodysplastic Syndrome)
01/2022 - 01/2018
2Anemia
07/2021 - 11/2005
2Nausea
11/2005 - 11/2005
2Alopecia (Baldness)
11/2005 - 11/2005
1Carcinoma (Carcinomatosis)
05/2012
1Diarrhea
11/2005
1Anorexia
11/2005
1Edema (Dropsy)
11/2005
1Melanoma (Melanoma, Malignant)
11/2005
1Ileus
11/2005
1Neutropenia
11/2005
1Peripheral Nervous System Diseases (PNS Diseases)
11/2005
1Vomiting
11/2005

Drug/Important Bio-Agent (IBA)

22- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
05/2012 - 11/2009
2XMT 1001IBA
05/2012 - 11/2009
2Irinotecan (Camptosar)FDA LinkGeneric
05/2012 - 11/2009
2CamptothecinIBA
05/2012 - 11/2009
2Pharmaceutical PreparationsIBA
05/2012 - 11/2005
2tasidotinIBA
11/2005 - 11/2005
1Azacitidine (5 Azacytidine)FDA Link
01/2022
1pevonedistatIBA
01/2022
1SolutionsIBA
07/2021
1Topoisomerase I InhibitorsIBA
05/2012
1ProdrugsIBA
11/2009
1Aspartic Acid (Aspartate)FDA Link
11/2005
1Alanine Transaminase (SGPT)IBA
11/2005
1Transaminases (Aminotransferases)IBA
11/2005

Therapy/Procedure

2Drug Therapy (Chemotherapy)
01/2018 - 01/2018
1Hematopoietic Stem Cell Transplantation
01/2018